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pmaip1 (noxa) rabbit polyclonal antibody  (Santa Cruz Biotechnology)


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    Structured Review

    Santa Cruz Biotechnology pmaip1 (noxa) rabbit polyclonal antibody
    SOX30 accelerates expression of p53 signaling pathway-related genes. ( a ) Ectopic expression of SOX30 significantly ( P <0.01) enhances endogenous expression of P53, P21, BAX and <t>PMAIP1</t> in A549 and H460 cells. The mRNA expression was examined by qRT–PCR, and ACTIN was used as an internal control. * P <0.05; ** P <0.01. ( b ) The protein levels of P53, P21, BAX and PMAIP1 were detected by WB after restoration of SOX30 in A549 and H460 cells. ACTIN was used as an internal control. ( c , d ) The mRNA and protein expression levels of SOX30 and P53 in xenograft tumors were examined by qRT–PCR and WB. ACTIN was used as an internal control. ( e ) SOX30 increases the number of terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL)-positive H460 cells in xenograft tumors. Two (1 and 2) representative images were randomly selected from each sample (H460-vector and H460-SOX30). The arrows indicate apoptotic cells.
    Pmaip1 (Noxa) Rabbit Polyclonal Antibody, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 90/100, based on 157 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/pmaip1 (noxa) rabbit polyclonal antibody/product/Santa Cruz Biotechnology
    Average 90 stars, based on 157 article reviews
    pmaip1 (noxa) rabbit polyclonal antibody - by Bioz Stars, 2026-02
    90/100 stars

    Images

    1) Product Images from "SOX30, a novel epigenetic silenced tumor suppressor, promotes tumor cell apoptosis by transcriptional activating p53 in lung cancer"

    Article Title: SOX30, a novel epigenetic silenced tumor suppressor, promotes tumor cell apoptosis by transcriptional activating p53 in lung cancer

    Journal: Oncogene

    doi: 10.1038/onc.2014.370

    SOX30 accelerates expression of p53 signaling pathway-related genes. ( a ) Ectopic expression of SOX30 significantly ( P <0.01) enhances endogenous expression of P53, P21, BAX and PMAIP1 in A549 and H460 cells. The mRNA expression was examined by qRT–PCR, and ACTIN was used as an internal control. * P <0.05; ** P <0.01. ( b ) The protein levels of P53, P21, BAX and PMAIP1 were detected by WB after restoration of SOX30 in A549 and H460 cells. ACTIN was used as an internal control. ( c , d ) The mRNA and protein expression levels of SOX30 and P53 in xenograft tumors were examined by qRT–PCR and WB. ACTIN was used as an internal control. ( e ) SOX30 increases the number of terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL)-positive H460 cells in xenograft tumors. Two (1 and 2) representative images were randomly selected from each sample (H460-vector and H460-SOX30). The arrows indicate apoptotic cells.
    Figure Legend Snippet: SOX30 accelerates expression of p53 signaling pathway-related genes. ( a ) Ectopic expression of SOX30 significantly ( P <0.01) enhances endogenous expression of P53, P21, BAX and PMAIP1 in A549 and H460 cells. The mRNA expression was examined by qRT–PCR, and ACTIN was used as an internal control. * P <0.05; ** P <0.01. ( b ) The protein levels of P53, P21, BAX and PMAIP1 were detected by WB after restoration of SOX30 in A549 and H460 cells. ACTIN was used as an internal control. ( c , d ) The mRNA and protein expression levels of SOX30 and P53 in xenograft tumors were examined by qRT–PCR and WB. ACTIN was used as an internal control. ( e ) SOX30 increases the number of terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL)-positive H460 cells in xenograft tumors. Two (1 and 2) representative images were randomly selected from each sample (H460-vector and H460-SOX30). The arrows indicate apoptotic cells.

    Techniques Used: Expressing, Quantitative RT-PCR, End Labeling, TUNEL Assay, Plasmid Preparation



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    pmaip1 (noxa) rabbit polyclonal antibody  (Santa Cruz Biotechnology)
    90
    Santa Cruz Biotechnology pmaip1 (noxa) rabbit polyclonal antibody
    SOX30 accelerates expression of p53 signaling pathway-related genes. ( a ) Ectopic expression of SOX30 significantly ( P <0.01) enhances endogenous expression of P53, P21, BAX and <t>PMAIP1</t> in A549 and H460 cells. The mRNA expression was examined by qRT–PCR, and ACTIN was used as an internal control. * P <0.05; ** P <0.01. ( b ) The protein levels of P53, P21, BAX and PMAIP1 were detected by WB after restoration of SOX30 in A549 and H460 cells. ACTIN was used as an internal control. ( c , d ) The mRNA and protein expression levels of SOX30 and P53 in xenograft tumors were examined by qRT–PCR and WB. ACTIN was used as an internal control. ( e ) SOX30 increases the number of terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL)-positive H460 cells in xenograft tumors. Two (1 and 2) representative images were randomly selected from each sample (H460-vector and H460-SOX30). The arrows indicate apoptotic cells.
    Pmaip1 (Noxa) Rabbit Polyclonal Antibody, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/pmaip1 (noxa) rabbit polyclonal antibody/product/Santa Cruz Biotechnology
    Average 90 stars, based on 1 article reviews
    pmaip1 (noxa) rabbit polyclonal antibody - by Bioz Stars, 2026-02
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    SOX30 accelerates expression of p53 signaling pathway-related genes. ( a ) Ectopic expression of SOX30 significantly ( P <0.01) enhances endogenous expression of P53, P21, BAX and PMAIP1 in A549 and H460 cells. The mRNA expression was examined by qRT–PCR, and ACTIN was used as an internal control. * P <0.05; ** P <0.01. ( b ) The protein levels of P53, P21, BAX and PMAIP1 were detected by WB after restoration of SOX30 in A549 and H460 cells. ACTIN was used as an internal control. ( c , d ) The mRNA and protein expression levels of SOX30 and P53 in xenograft tumors were examined by qRT–PCR and WB. ACTIN was used as an internal control. ( e ) SOX30 increases the number of terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL)-positive H460 cells in xenograft tumors. Two (1 and 2) representative images were randomly selected from each sample (H460-vector and H460-SOX30). The arrows indicate apoptotic cells.

    Journal: Oncogene

    Article Title: SOX30, a novel epigenetic silenced tumor suppressor, promotes tumor cell apoptosis by transcriptional activating p53 in lung cancer

    doi: 10.1038/onc.2014.370

    Figure Lengend Snippet: SOX30 accelerates expression of p53 signaling pathway-related genes. ( a ) Ectopic expression of SOX30 significantly ( P <0.01) enhances endogenous expression of P53, P21, BAX and PMAIP1 in A549 and H460 cells. The mRNA expression was examined by qRT–PCR, and ACTIN was used as an internal control. * P <0.05; ** P <0.01. ( b ) The protein levels of P53, P21, BAX and PMAIP1 were detected by WB after restoration of SOX30 in A549 and H460 cells. ACTIN was used as an internal control. ( c , d ) The mRNA and protein expression levels of SOX30 and P53 in xenograft tumors were examined by qRT–PCR and WB. ACTIN was used as an internal control. ( e ) SOX30 increases the number of terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL)-positive H460 cells in xenograft tumors. Two (1 and 2) representative images were randomly selected from each sample (H460-vector and H460-SOX30). The arrows indicate apoptotic cells.

    Article Snippet: Primary antibodies were SOX30 rabbit polyclonal antibody (1:1000; Santa Cruz Biotechnology), p53 mouse polyclonal antibody (1:1000; Santa Cruz Biotechnology), BAX rabbit polyclonal antibody (1:1000; Santa Cruz Biotechnology), P21 rabbit polyclonal antibody (1:1000; Cell Signaling Technology, Boston, MA, USA) and PMAIP1 (NOXA) rabbit polyclonal antibody (1:1000; Santa Cruz Biotechnology).

    Techniques: Expressing, Quantitative RT-PCR, End Labeling, TUNEL Assay, Plasmid Preparation